Diffuse Large B-Cell Lymphoma with Mass Lesions of Skull Vault and Ileocecum
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- Kosugi Shigeki
- Department of Internal Medicine, Division of Hematology and Oncology, St. Marianna University School of Medicine
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- Kume Masaaki
- The Second Department of Internal Medicine, Hiraka General Hospital
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- Sato Joji
- Department of Internal Medicine, Sato Hospital
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- Sakuma Ikuo
- Division of Radiology, Department of Medicine, Akita University School of Medicine
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- Moroi Junta
- Department of Neurosurgery, Research Institute for Brain and Blood Vessels-Akita
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- Izumi Keiichi
- Department of Surgery, Sato Hospital
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- Sato Yasukazu
- Department of Surgery, Sato Hospital
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- Nakamura Naoya
- Department of Pathology, Tokai University School of Medicine
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- Takahashi Masatomo
- Department of Internal Medicine, Division of Hematology and Oncology, St. Marianna University School of Medicine
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- Miura Ikuo
- Department of Internal Medicine, Division of Hematology and Oncology, St. Marianna University School of Medicine
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抄録
We report a rare case of non-Hodgkin lymphoma with mass lesions of skull vault and ileocecum. The patient was an 82-year-old Japanese woman who exhibited a painless subcutaneous scalp tumor in the right parietal region associated with no neurological abnormalities. Magnetic resonance imaging of the head demonstrated a mass in the skull vault with iso- to hypointense signals on both T1- and T2-weighted imaging. Biopsy of the mass revealed that the tumor comprised large cells that were immunoreactive for CD20 (L-26) and CD79a. Diffuse large B-cell lymphoma (DLBCL) was therefore diagnosed. Further investigation could not identify any other evidence of systemic lymphoma other than ileocecal lesions. She was treated by irradiation (45 Gy) of the mass on the parietal bone and with rituximab, pirarubicin, cyclophosphamide, and vincristine. The patient achieved complete remission after 3 cycles of systemic chemotherapy. As of 30 months after presentation, no signs of lymphoma have been found. [J Clin Exp Hematop 53(3) : 215-219, 2013]
収録刊行物
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- Journal of Clinical and Experimental Hematopathology
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Journal of Clinical and Experimental Hematopathology 53 (3), 215-219, 2013
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詳細情報
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- CRID
- 1390282679681604096
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- NII論文ID
- 130003383996
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- COI
- 1:STN:280:DC%2BC2czgtV2mtg%3D%3D
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- ISSN
- 18809952
- 13464280
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- PubMed
- 24369223
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可