An Autopsy Case of Malignant Pleural Mesothelioma Associated with Nephrotic Syndrome

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Author(s)

    • Toyoshima Mikio
    • Department of Respiratory Medicine, Hamamatsu Rosai Hospital, Japan
    • Nihashi Fumiya
    • Department of Respiratory Medicine, Hamamatsu Rosai Hospital, Japan
    • Tsukui Hiroe
    • Department of Diagnostic Pathology, Hamamatsu University School of Medicine, Japan
    • Baba Satoshi
    • Department of Diagnostic Pathology, Hamamatsu University School of Medicine, Japan
    • Sugimura Haruhiko
    • Department of Tumor Pathology, Hamamatsu University School of Medicine, Japan
    • Suda Takafumi
    • The Second Department of Internal Medicine, Hamamatsu University School of Medicine, Japan

Abstract

A 64-year-old man who had been exposed to asbestos was referred to our hospital for a detailed examination of left pleural effusion. A laboratory examination of the urine and blood revealed nephrotic syndrome. A thoracoscopic examination did not yield a definitive diagnosis. Twenty months later, a left pleural tumor became apparent, and the patient died of respiratory failure and cachexia. An autopsy revealed epithelioid malignant pleural mesothelioma. The glomeruli appeared normal under light microscopy. A review of the English literature revealed only three reports of malignant mesothelioma associated with minimal-change nephrotic syndrome. The natural course of malignant mesothelioma with nephrotic syndrome has not been previously reported.<br>

Journal

  • Internal Medicine

    Internal Medicine 53(3), 243-246, 2014

    The Japanese Society of Internal Medicine

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