Pulmonary Microvascular Remodeling after Balloon Pulmonary Angioplasty in a Patient with Chronic Thromboembolic Pulmonary Hypertension
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- Ogawa Aiko
- Department of Clinical Science, National Hospital Organization Okayama Medical Center, Japan
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- Kitani Masashi
- Department of Clinical Pathology, National Hospital Organization Okayama Medical Center, Japan
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- Mizoguchi Hiroki
- Division of Cardiology, National Hospital Organization Okayama Medical Center, Japan
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- Munemasa Mitsuru
- Division of Cardiology, National Hospital Organization Okayama Medical Center, Japan
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- Matsuo Kiyoshi
- Department of Respiratory Medicine, National Hospital Organization Okayama Medical Center, Japan
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- Yamadori Ichiro
- Department of Clinical Pathology, National Hospital Organization Okayama Medical Center, Japan
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- Andou Akio
- Department of Chest Surgery, National Hospital Organization Okayama Medical Center, Japan
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- Matsubara Hiromi
- Department of Clinical Science, National Hospital Organization Okayama Medical Center, Japan Division of Cardiology, National Hospital Organization Okayama Medical Center, Japan
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Abstract
We herein report a case of peripheral type chronic thromboembolic pulmonary hypertension treated with medical therapy and subsequent balloon pulmonary angioplasty (BPA). After a series of BPA procedures, the patient's hemodynamics almost completely normalized. The patient was later diagnosed with lung carcinoma, and the vasculature of the resected lung demonstrated intimal thickening and luminal stenosis in the pulmonary arteries in both the areas where BPA was performed and not performed, in spite of a marked reduction in pulmonary arterial pressure. The present case is the first report on the histology of the pulmonary vasculature following BPA.<br>
Journal
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- Internal Medicine
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Internal Medicine 53 (7), 729-733, 2014
The Japanese Society of Internal Medicine