Comprehensive Analysis of Systemically Disseminated ST8/non-USA300 type Community-acquired Methicillin-resistant <i>Staphylococcus aureus</i> Infection
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- Hagiya Hideharu
- Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan Emergency Unit and Critical Care Center, Tsuyama Central Hospital, Japan
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- Hisatsune Junzo
- Project Research Center for Nosocomial Infectious Diseases, Hiroshima University, Japan Department of Bacteriology, Hiroshima University Graduate School of Biochemical and Health Sciences, Japan
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- Kojima Taro
- Project Research Center for Nosocomial Infectious Diseases, Hiroshima University, Japan Department of Bacteriology, Hiroshima University Graduate School of Biochemical and Health Sciences, Japan
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- Shiota Sumiko
- Department of Pathogenic Microbiology, School of Pharmacy, Shujitsu University, Japan
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- Naito Hiromichi
- Emergency Unit and Critical Care Center, Tsuyama Central Hospital, Japan
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- Hagioka Shingo
- Emergency Unit and Critical Care Center, Tsuyama Central Hospital, Japan
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- Morimoto Naoki
- Emergency Unit and Critical Care Center, Tsuyama Central Hospital, Japan
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- Otsuka Fumio
- Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan
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- Sugai Motoyuki
- Project Research Center for Nosocomial Infectious Diseases, Hiroshima University, Japan Department of Bacteriology, Hiroshima University Graduate School of Biochemical and Health Sciences, Japan
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抄録
Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) is genetically heterogeneous and various genotypes are spreading worldwide. We herein report a case of systematically disseminated Japan-intrinsic CA-MRSA infection that was successfully treated. A genetically identical single strain was isolated from a total of 11 different parts of the patient's body, and the pathogen was found to be multilocus sequence type 8, staphylococcal cassette chromosome mec IV, coagulase type III and negative for both Panton-Valentine leukocidin and arginine catabolic mobile element. The epidemiology and pathogenicity of the Japan-intrinsic CA-MRSA strain remain unknown, and further investigation of this life-threatening organism is warranted.<br>
収録刊行物
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- Internal Medicine
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Internal Medicine 53 (8), 907-912, 2014
一般社団法人 日本内科学会