合成化学者による生命現象解明へのアプローチ~生体直交型反応の開発~ Bioorthogonal Reactions for Biomolecular Functionalization and Imaging

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Investigating the function of native biomolecules is an important but challenging task due to the highly complex nature of biological systems. To understand complex biological systems in terms of simple biomolecular interactions, organic chemists have developed many bioorthogonal reactions over the past few years. These bioorthogonal reactions have been applied for the efficient construction of functionalized biomolecules. In this mini review, the development and the applications of such bioorthogonal reactions are described.

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  • 有機合成化学協会誌

    有機合成化学協会誌 72(3), 303-304, 2014

    社団法人 有機合成化学協会

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