Craniofacial Development in Rats Fed on Powdered Diet Following Extraction of All Upper Molars

  • Abo Norioki
    Department of Pediatric Dentistry, Nihon University School of Dentistry at Matsudo, Matsudo, Chiba 271-8587, Japan
  • Ogawa Kei
    Department of Pediatric Dentistry, Nihon University School of Dentistry at Matsudo, Matsudo, Chiba 271-8587, Japan
  • Shimizu Kunihiko
    Department of Pediatric Dentistry, Nihon University School of Dentistry at Matsudo, Matsudo, Chiba 271-8587, Japan

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タイトル別名
  • <b>Craniofacial Development in Rats Fed on Powdered Diet Following Extraction of All Upper Molars </b>

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抄録

Growth of the craniofacial bone is a complex biological phenomenon induced by highly coordinated interaction between genetic and environmental factors. The purpose of this study was to confirm whether the environmental factors, namely powdered diet and extraction of all upper molars, have an influence on the cranium and mandibular bone size,bone volume, mineral bone density, widths between left and right condyles and gonions,and intra-arch widths at the first and third molars in rat mandibles.<br> Ten 5-week-old male Wister rats were fed on powdered diet after extraction of all upper molars (experimental group=5 rats) and pellet diet without extraction of molars (control group=5 rats) for 20 weeks. At 20 weeks of age, the animals were examined by Microcomputer tomography. The mean values of the measurements in the two groups were compared.<br> There was no significant difference between the groups in the cranial sizes. The vertical lengths were significantly shorter in the experiment group than the control group while no significant difference was observed in the mandibular horizontal lengths and widths at the left and right condyles and gonions. The mandibular volume and bone mineral density in the experimental group were significantly lower than that of the control group. The intraarch width at the lower third molars was also significantly shorter in the experimental group than the control group.

収録刊行物

  • IJOMS

    IJOMS 12 (3), 129-140, 2014

    日本大学松戸歯学部 口腔科学研究所

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