カビ由来 ラクターゼについて
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- 後藤 真孝
- 天野エンザイム株式会社
書誌事項
- タイトル別名
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- Fungal lactase
- カビ ユライ ラクターゼ ニ ツイテ
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Lactose intolerant people in Asia are about 80% population. People with lactose intolerant do not produce enough of the lactase enzyme to break down lactose contained in milk and milk products. One method for prevention, reduction or improvement is lactase supplementation, and fungal lactase (β-galactosidase) is used generally. Characteristics of fungal lactase is stability at acidic pH. Acidic stability of three lactases produced by Aspergillus oryzae, Penicillium multicolor and Aspergillus niger are different. Lactase from A. niger is most stable among them, but low-reactivity at neutral pH. Amino acid sequence homology among three fungal lactases is more than 70%, but relation between lactase character and structure is unknown. In Japan, lactase for lactose intolerance is regulated as drug and it is hard to purchase generally. A. oryzae is known as ‘Koji’ used for japanese traditional fermented foods such as miso, syoyu and sake. For this reason, lactase produced by A. oryzae is thought to be safe. If lactase can be obtained like U.S. dietary supplement, it is expected that lactase supplementation will be known widely.
収録刊行物
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- ミルクサイエンス
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ミルクサイエンス 61 (3), 239-245, 2012
日本酪農科学会
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詳細情報 詳細情報について
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- CRID
- 1390001205510039680
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- NII論文ID
- 130003398724
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- NII書誌ID
- AA11125739
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- COI
- 1:CAS:528:DC%2BC3sXhs1Cqurw%3D
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- ISSN
- 21880700
- 13430289
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- NDL書誌ID
- 024216966
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- IRDB
- NDL
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可