Aggregation of Tobacco Mosaic Virus by Sodium Chondroitin Sulfate
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- SANO Yoh
- Institute for Plant Virus Research, Tsukuba Science City
抄録
The precipitation of tobacco mosaic virus by sodium chondroitin sulfate in an aqueous solution was investigated kinetically by means of turbidimetry. The virus solution became turbid after the addition of chondroitin sulfate. A threshold concentration of chondroitin, 1.33 mg/ml, was required for virus precipitation, irrespective of the virus concentration. The precipitation resulted from a mutual spatial exclusion phenomenon, leading to the separation of the virus as a crystalline phase. The dimension of chondroitin sulfate calculated at the threshold concentration agreed well with that obtained by other methods. The initial slopes and the aggregation half-times of the virus aggregates depended on both chondroitin and virus concentrations and the former increased with the increase in concentration of each. Above the threshold concentration of chondroitin sulfate, tobacco mosaic virus aggregation was a rapid-aggregation process and ended within 100 sec.
収録刊行物
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- MICROBIOLOGY and IMMUNOLOGY
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MICROBIOLOGY and IMMUNOLOGY 24 (11), 1035-1042, 1980
Center For Academic Publications Japan
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詳細情報 詳細情報について
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- CRID
- 1570572703128518400
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- NII論文ID
- 130003482890
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- ISSN
- 03855600
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- 本文言語コード
- en
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- データソース種別
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- CiNii Articles