Monoclonal and Oligoclonal Immunoglobulins Localized in Human Dental Periapical Lesion

• MATSUMOTO Yukihiro

  Second Department of Oral and Maxillofacial Surgery, Tsurumi University

抄録

The gamma-globulin fractions of extracts obtained from 70 periapical lesions were studied by agarose gel electrophoresis and immunofixation. In agarose gel electrophoresis, homogeneous bands in the gamma-globulin region were found in 25 of 70 specimens (36%). Among the 25 specimens showing homogeneous bands, these bands in six specimens were identified as monoclonal or oligoclonal immunoglobulins. Local production of oligoclonal immunoglobulins was suggested since the corresponding homogeneous bands were not detected in the serum of the same patient. These immunoglobulins may be produced as a result of local immunogenic response against infecting bacteria in periapical inflammation.

収録刊行物

• MICROBIOLOGY and IMMUNOLOGY

  MICROBIOLOGY and IMMUNOLOGY 29 (8), 751-757, 1985

  Center For Academic Publications Japan

詳細情報

• CRID: 1571135653080905600
• NII論文ID: 130003483164
• ISSN: 03855600
• Web Site: https://jlc.jst.go.jp/DN/JALC/00170427942?from=CiNii
• 本文言語コード: en
• データソース種別:
  • CiNii Articles