Specific Immunoglobulin Response in Mice Immunized with Porins and Challenged with <i>Salmonella typhi</i>

J-STAGE
  • SHARMA Praveen
    Department of Experimental Medicine, Internal Medicine, Postgraduate Institute of Medical Education and Research
  • GANGULY Nirmal Kumar
    Department of Experimental Medicine, Internal Medicine, Postgraduate Institute of Medical Education and Research
  • SHARMA Bal Krishan
    Department of Experimental Medicine, Internal Medicine, Postgraduate Institute of Medical Education and Research
  • SHARMA Saroj
    Department of Microbiology, Punjab University
  • SEHGAL Rakesh
    Department of Experimental Medicine, Internal Medicine, Postgraduate Institute of Medical Education and Research

抄録

Specific antiporin antibody (IgG, IgM, and IgA) response was studied in control, infected, immunized-infected, and immunized mice. The activity of specific IgG immunoglobulins was found to be the highest in immunized and immunized-infected groups in which 87.5% protection had been observed by laboratory potency test in mice; the next-highest activities were those of IgM and IgA immunoglobulins. However, in the infected group the activity of specific IgM and IgG immunoglobulins was almost similar.

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