Drug Resistance and R Plasmids in <i>Pasteurella multocida</i> Isolates from Swine

• YAMAMOTO Junya

  Zen-noh Institute of Animal Health

• SAKANO Tetsuya

  Zen-noh Institute of Animal Health

• SHIMIZU Mikio

  Zen-noh Institute of Animal Health

Abstract

A total of 163 strains of Pasteurella multocida isolated from swine were examined for drug resistance and R plasmids. Strains resistant to sulfadimethoxine (Sa^r), ampicillin (Ap^r), streptomycin (Sm^r), kanamycin (Km^r), and chloramphenicol (Cp^r) were found in 93.9, 1.8, 16.6, 1.2, and 10.4%, respectively. There were two patterns of drug resistance (Sa^r and Sa^rCp^r) in isolates from nasal cavities, and five patterns (Sa^r, Sa^rSm^r, Sa^rSm^rCp^r, Sa^rSm^rAp^r, and Sa^rSm^rKm^rCp^r) in isolates from pneumonic lung specimens. Two isolates studied were proved to carry a nonconjugative R plasmid pJY2 or pJY8 with other unidentified plasmids, respectively. pJY2 (3.6 megadaltons) encoding resistance to Sa^rSm^r had one cleavage site for EcoRI or HindIII endonuclease and two sites for PstI endonuclease. pJY8 (5.5 megadaltons) encoding resistance to Sa^r Sm^rKm^rCp^r had one EcoRI site and two PstI sites.

Journal

• Japanese Journal of Microbiology

  Japanese Journal of Microbiology 34 (9), 715-721, 1990

  Center For Academic Publications Japan

Details

• CRID: 1573105977918803456
• NII Article ID: 130003483694
• ISSN: 03855600
• Web Site: https://jlc.jst.go.jp/DN/JALC/00076994579?from=CiNii
• Text Lang: en
• Data Source:
  • CiNii Articles