Relationship between an 85kDa Protein and the Protective Effects of <i>Mycoplasma pneumoniae</i>

• YAYOSHI Masami

  Urawa Gakuin

• SASAKI Tsuguo

  National Institute of Health

• YOSHIOKA Morimasa

  Tokyo Women's Medical College

抄録

In the immunoblot analysis, sera from patients infected with Mycoplasma pneumoniae reacted with the 168kDa (P1) and the 85kDa proteins of virulent strain FH-P24 and P24-S1 mutant strain but not with the 85kDa protein of P24-S11. Sera of hamsters and BALB/c mice, which had been immunized with live vaccines, were tested. In FH-P24 immunized animals, 100% or 80%, and in P24-S1, 40% of hamsters and 60% of BALB/c mice, developed antibodies against the 85kDa protein, but antibodies were not detected in sera of P24-S11 immunized animals. The correlation between the development of antibodies to 85kDa protein in the sera of vaccinated animals and the effects of protection by living vaccines were suggested.

収録刊行物

• MICROBIOLOGY and IMMUNOLOGY

  MICROBIOLOGY and IMMUNOLOGY 36 (5), 455-464, 1992

  Center For Academic Publications Japan

詳細情報

• CRID: 1571135653080935808
• NII論文ID: 130003483878
• ISSN: 03855600
• Web Site: https://jlc.jst.go.jp/DN/JALC/00078685376?from=CiNii
• 本文言語コード: en
• データソース種別:
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