Small, Round-Structured Viruses (SRSVs) Associated with Acute Gastroenteritis Outbreaks in Gifu, Japan

J-STAGE
  • Kawamoto Hiroyoshi
    Division of Virology, Department of Health Science, Gifu Prefectural Health and Environment Research Center
  • Hasegawa Sumiyo
    Department of Virology, Toyama Institute of Health
  • Sawatari Seiko
    Division of Virology, Department of Health Science, Gifu Prefectural Health and Environment Research Center
  • Miwa Chieko
    Division of Virology, Department of Health Science, Gifu Prefectural Health and Environment Research Center
  • Morita Osayuki
    Department of Virology, Toyama Institute of Health
  • Hosokawa Takehiko
    Internal Medicine, Tokai Central Hospital of the Mutual Aid Association of Public School Teachers
  • Tanaka Hiroshi
    Department of Pediatrics, Prefectural Gifu Hospital

抄録

Two outbreaks of non-bacterial gastroenteritis occurred in Gifu prefecture in January 1989 and in January 1991. Both outbreaks were closely related to the consumption of raw oysters, and showed similar clinical features. Small, round-structured virus particles were found in patient stools in both outbreaks by electron microscopy. The role of these particles as the causative agents of the outbreaks were strongly suggested by immune electron microscopy and/or western-blotting immunoassay. When compared with SRSV-9 (Tokyo/SRSV/86-510) reported previously (Hayashi et al, J. Clin. Microbiol., 27: 1728-1733, 1989), it was found that these viral particles were antigenically similar to SRSV-9, and had a major structural protein of 63 kilodaltons (kDa). Further, the prevalence of this agent in Gifu area was examined by western blot antibody assay using 67 serum samples collected from the inhabitants in 1991. The results indicated the circulation of the same or antigenically similar agent in this area.

収録刊行物

詳細情報 詳細情報について

問題の指摘

ページトップへ