A Flow Cytometric Assay Reveals a Suppression of Phagocytosis by Rabbit Defensin NP-3A in Mouse Peritoneal Macrophages

• Ichinose Mitsuyuki

  Department of Physiology, Shimane Medical University

• Sawada Masashi

  Department of Physiology, Shimane Medical University

抄録

Phagocytosis of fluorescein isothiocyanate (FITC)-labeled polystyrene microparticles by peritoneal macrophages from thioglycollate-elicited mice was examined by means of flow cytometry (FCM). This assay revealed that rabbit defensin NP-3A suppressed the phagocytosis in a dose-dependent manner. The present results suggest that NP-3A released from neutrophils is one of the mediators which modulates the activity of macrophages in response to infection.

収録刊行物

• MICROBIOLOGY and IMMUNOLOGY

  MICROBIOLOGY and IMMUNOLOGY 39 (5), 365-367, 1995

  Center For Academic Publications Japan

詳細情報

• CRID: 1573105977918669568
• NII論文ID: 130003484243
• ISSN: 03855600
• Web Site: https://jlc.jst.go.jp/DN/JALC/00081506927?from=CiNii
• 本文言語コード: en
• データソース種別:
  • CiNii Articles