Low Renin Hypertension - Is It a Stage of Essential Hypertension?
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- ABE KEISHI
- Second Department of Internal Medicine, Tohokat University School of Medicine
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- IROKAWA NOBUO
- Second Department of Internal Medicine, Tohokat University School of Medicine
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- AOYAGI HARUKI
- Second Department of Internal Medicine, Tohokat University School of Medicine
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- SEINO MASAHIDE
- Second Department of Internal Medicine, Tohokat University School of Medicine
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- YASUJIMA MINORU
- Second Department of Internal Medicine, Tohokat University School of Medicine
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- RITZ KANCHO
- Second Department of Internal Medicine, Tohokat University School of Medicine
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- ITO TORU
- Second Department of Internal Medicine, Tohokat University School of Medicine
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- CHIBA SATORU
- Second Department of Internal Medicine, Tohokat University School of Medicine
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- SAKURAI YUTAKA
- Second Department of Internal Medicine, Tohokat University School of Medicine
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- SAITO KEITARO
- Second Department of Internal Medicine, Tohokat University School of Medicine
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- KUSAKA TAKASHI
- Second Department of Internal Medicine, Tohokat University School of Medicine
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- OTSUKA YOICHI
- Second Department of Internal Medicine, Tohokat University School of Medicine
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- MIYAZAKI SEIZI
- Second Department of Internal Medicine, Tohokat University School of Medicine
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- YOSHINAGA KAORU
- Second Department of Internal Medicine, Tohokat University School of Medicine
書誌事項
- タイトル別名
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- Low Renin Hypertension Is It a Stage of
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抄録
Resting plasma renin activity (PRA) and PRA after the load of furosemide i. v. and two-hour's upright posture were studied on 139 healthy normotensive subjects and 200 patients with essential hypertension. Regarding the age factor, the estimated values in control subjects were very low in the advanced ages over 60 years, while no significant differences were found in the subjects aged from 20 to 59 years. In essential hypertension, a similar relationship between renin and aging was observed. The patients with essential hypertension were classified into 3 groups according to the resting PRA values; low, normal and high. There were no signi-ficant differences among the. 3 groups concerning the mean ages and the blood pressure. Regarding the incidence of low PRA hypertension at different ages there were no significant differences among the decades ander 60 years of age. On the other hand, all hypertensive patients were classified into 3 groups according to their responses of renin secretion; low responders, normal responders, and high res-ponders. There was a positive correlation between the incidences of hyporesponders of renin secretion and the age. Higher incidences of hyporesponders were obtained in older patients. The incidence of hyperresponders was higher in younger patients than in older patients. Our study revealed that the incidences of low resting PRA were similar in each decade under 60 years, and it seems unlikely that low renin hypertension is a stage in a long-term course of essential hypertension. On the contrary, the hyporesponders of renin secretion to the load are apparently related to the age. It is concluded that low PRA essential hypertension must be distinct from the hyporesponder of renin secretion.
収録刊行物
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- The Tohoku Journal of Experimental Medicine
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The Tohoku Journal of Experimental Medicine 121 (4), 347-354, 1977
東北ジャーナル刊行会
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詳細情報 詳細情報について
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- CRID
- 1390282679218395520
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- NII論文ID
- 130003492311
- 40005306067
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- NII書誌ID
- AA00863920
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- COI
- 1:CAS:528:DyaE2sXkt1Shs78%3D
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- ISSN
- 13493329
- 00408727
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- NDL書誌ID
- 1819887
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- PubMed
- 867421
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可