Effect of estrogen upon the juxtaglomerular apparatus and the renin-angiotensin system in rats.
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- KONDO KAZUOKI
- Department of Internal Medicine, University of Keio School of Medicine
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- MISUMI JIRO
- Department of Internal Medicine, University of Keio School of Medicine
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- NAKAMURA RYUICHI
- Department of Internal Medicine, University of Keio School of Medicine
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- SAITO IKUO
- Department of Internal Medicine, University of Keio School of Medicine
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- SARUTA TAKAO
- Department of Internal Medicine, University of Keio School of Medicine
書誌事項
- タイトル別名
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- Effect of Estrogen upon the Juxtaglomer
この論文をさがす
抄録
Administration of 1.5mg/kg of estriol intramuscularly and 15mg/kg of stilbestrol disulfate intraperitoneally daily for 15 days caused an increase in plasma renin substrate (PRS), accompanied by an increase in plasma renin activity (PRA) and a slight decrease in plasma renin concentration (PRC). Contrary to the slight suppres-sion of PRC, juxtaglomerular granulation index (JGI) was significantly increased in rats treated by estrogen. In the rats which developed hypertension by estrogen, PRA, PRC and JGI were a little higher than those in the rats which remained normotensive after the same estrogon treatment, but these differences were not statistically significant. Therefore, it seems rather difficult to attribute the development of estrogen hypertension only to the quantitative changes in the renin-angiotensin system.
収録刊行物
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- The Tohoku Journal of Experimental Medicine
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The Tohoku Journal of Experimental Medicine 126 (3), 267-272, 1978
東北ジャーナル刊行会
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詳細情報 詳細情報について
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- CRID
- 1390282679217951232
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- NII論文ID
- 130003492508
- 40005305857
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- NII書誌ID
- AA00863920
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- COI
- 1:CAS:528:DyaE1MXhs1yhsw%3D%3D
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- ISSN
- 13493329
- 00408727
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- NDL書誌ID
- 1969360
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- PubMed
- 734651
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可