Toxic Substances in Cancer

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  • IV. On a Factor in Gastric Carcinoma Tissue Inhibiting the Catalase Activity of the Mouse Liver

抄録

Various fractions were prepared from the tissue of gastric carcinoma, and tested for inhibition of the catalase activity of the mouse liver by Warburg's manometric method.<br> 1. The aqueous extract of gastric carcinoma was effective at as small a dose as 10mg., whereas the minimum effective dose in the case of normal gastric mucosa was 30mg.<br> 2. Of the various gastric carcinoma extracts tested, the fraction that was mainly composed of nucleoprotein was most effective, the minumum effective dose being as small as 1mg.

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