UDP-N-methyl-D-glucosamine-phosphate - a possible intermediate of N-methyl-L-glucosamine moiety of streptomycin.

Access this Article

Author(s)

Abstract

The formation of <i>N</i>-methyl-L-glucosamine moiety of streptomycin from n-glucosamine by <i>Streptomyces griseus</i> was studied. The addition of thymine to the culture medium stimulated the formation of streptomycin and the incorporation of D-glucosamine into <i>N</i>-methyl-L-glucosamine moiety. During a study of sugar nucleotides in the mycelia, a novel UDP-amino sugar was isolated. The compound was formed before the maximum production of streptomycin. It was UDP-<i>N</i>-methyl-n-glucosamine-phosphate.

Journal

  • The Journal of Antibiotics

    The Journal of Antibiotics 35(11), 1571-1577, 1982

    JAPAN ANTIBIOTICS RESEARCH ASSOCIATION

Codes

  • NII Article ID (NAID)
    130003500172
  • NII NACSIS-CAT ID (NCID)
    AA0069330X
  • Text Lang
    ENG
  • ISSN
    0021-8820
  • NDL Article ID
    2617117
  • NDL Source Classification
    SD0(薬学)
  • NDL Source Classification
    ZS51(科学技術--薬学)
  • NDL Call No.
    Z53-D224
  • Data Source
    NDL  J-STAGE 
Page Top