MECHANISM OF CYANIDE RESISTANCE IN ACHROMOBACTER:IV. CYANIDE RESISTANT RESPIRATION OF ANAEROBICALLY CULTIVATED CELLS
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1. <i>Achromobacter</i> strain 7, grown under anaerobic condition was found to possess greater amount of cytochrome a<sub>2</sub> than that grown under aerobic condition.<br> 2. Though the respiratory activities of both kinds of cells were quite equal, the anaerobically cultivated cells showed a higher respiratory activity than the aerobically cultivated cells, in the presence of cyanide (10<sup>-3</sup><i>M</i>); namely the respiration became cyanide resistant during an anaerobic cultivation.<br> 3. A parallelism was observed between the cytochrome a<sub>2</sub> content and the respiratory activity in the presence of cyanide.<br> 4. A physiological significance of cytochrome a<sub>2</sub> as respiratory carrier and the mechanism of cyanide resistance in anaerobically cultivated cells were discussed.<br> The authors wish to express their sincere appreciation to Dr. K. Sakaguchi for his encouragement and interest.
- J Biochem (Tokyo)
J Biochem (Tokyo) 48(2), 205-213, 1960
The Japanese Biochemical Society