肝細胞癌切除術後の再発に対する治療成績

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  • Clinical management for recurrence after resection of hepatocellular carcinoma.

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In 30 (65.2%) out of 46 cases undergoing hepatectomy for hepatocellular carcinoma (HCC) without absolute noncurative operation, the recurrence occurred. The thrapeutic outcomes in these 30 patients were assesed in reference to modes of recurrence. Patients with multiple recurrence in bilateral lobes or isolateral lobe of the remunant liver had significantly shorter intervals between the initial operation and recurrence compared to patients with other recurrence modes. Patients with multiple recurrence had mostly impaired liver function at the time of recurrence. The treatment for recurrence of HCC was selected based on the number of recurrent lesions and liver function. Local treatments such as hepatectomy, microwave coagulation therapy (MCT), percutaneus ethanol injection therapy (PEIT) were serected for patients with solitary recurrence, and transarterial treatment such as transarterial embolization (TAE) and transarterial infusion (TAI) for patients with multiple recurrence. There was no significant difference among recurrent locations in the cumulative survival rate after recurrence. However a significantly higher survival rate was noted in patients with solitary recurrence than in those with multiple recurrence.

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