蘇生後脳症における脳循環代謝

• 黒田 泰弘

  香川大学医学部附属病院救命救急センター

• 山下 進

  香川大学医学部附属病院救命救急センター

• 中村 丈洋

  香川大学医学部附属病院救命救急センター

• 河北 賢哉

  香川大学医学部附属病院救命救急センター

• 西山 佳宏

  香川大学医学部放射線科

• 河井 信行

  香川大学医学部脳神経外科

• 内野 博之

  東京医科大学八王子医療センター麻酔科

書誌事項

タイトル別名

• Cerebral Blood Flow and Metabolism Following Resuscitation from Cardiac Arrest

抄録

We reviewed the cerebral blood flow (CBF) and metabolism following resuscitation after cardiac arrest in humans measured by the Kety-Schmidt method, the washout method, or positron emission tomography and Safar's stage about neurologic outcome. The presence of stage I (no reflow) or stage II (early postischemic hyperemia) was not estimated because the CBF and metabolism could not measured within 1 hour following resuscitation after cardiac arrest. The CBF was reported to be decrease in stage III (delayed postischemic hypoperfusion) within 24 hours following resuscitation. Low metabolic rate for oxygen especially with poor outcome case was reported in stage III, on the contrary to Safar's stage which suggests normal or hypermetabolsim for oxygen with hypoperfusion. In the stage IV (after 24 hours after resuscitation), a case with transient hyperemia, sustained hypoperfusion, sustained hypometabolism was related to have a poor neurologic outcome. Cerebral metabolic rate for oxygen (CMRO₂) within 7 days after resuscitation cannot predict cerebral outcome in comatous patients after cardiac arrest because CMRO₂ was recovered after 7 days with a good outcome case.

収録刊行物

• 日本救急医学会雑誌

  日本救急医学会雑誌 17 (5), 167-176, 2006

  一般社団法人 日本救急医学会

キーワード

• 蘇生後脳症
• 脳グルコース消費量
• 脳酸素消費量
• 陽電子放出断層撮影法

詳細情報

• CRID: 1390282679345891200
• NII論文ID: 10018811070
• NII論文ID: 130003626041
• NII書誌ID: AN10284604
• DOI: 10.3893/jjaam.17.167
• ISSN: 18833772
• ISSN: 0915924X
• Web Site: https://search.jamas.or.jp/link/ui/2006245254
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
  • KAKEN
• 抄録ライセンスフラグ: 使用不可