書誌事項
- タイトル別名
-
- The Role of Macrophages in Saphenous Vein Graft Disease.
この論文をさがす
抄録
This study was designed to assess the role of macrophages in saphenous vein graft disease after coronary artery bypass grafting (CABG). Three newly harvested saphenous vein grafts (SVGs) and 6 SVGs removed from patients 8 to 15 years after CABG (3 were occluded soon after the operation and 3 became diseased after a long period) were immunostained for macrophages and investigated microscopically. No macrophages were detected in the newly harvested SVGs. In the grafts with early occlusion, macrophages were detected only in the superficial layer of the intima. In the grafts that became diseased after a long period, macrophage accumulation was detected at the site of atherosclerotic lesions. In the pathogenesis of arterial atherosclerotic lesions, vascular endothelial cell damage and subsequent subendothelial migration of monocytes/macrophages in the early phase are thought to be very important. This study revealed that macrophage migration into the intima of SVGs occurs soon after surgery and suggested it could be the basis of saphenous vein graft disease occurring long after CABG.
収録刊行物
-
- 日本心臓血管外科学会雑誌
-
日本心臓血管外科学会雑誌 29 (5), 295-298, 2000
特定非営利活動法人 日本心臓血管外科学会
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390282679681250944
-
- NII論文ID
- 130003629172
- 10009923266
-
- NII書誌ID
- AN00193284
-
- ISSN
- 18834108
- 02851474
-
- 本文言語コード
- ja
-
- データソース種別
-
- JaLC
- Crossref
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可