書誌事項
- タイトル別名
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- The Relationship between Airway Lesions and Pulmonary Function in Bronchial Asthma
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Relationships between airway lesions and pulmonary function were examined in forty-three patients with bronchial asthma with or without complications. The figure of airways and alveoli in asthma was examined by selective alveolo-bronchography (SAB). Spastic narrowing and stenosis at bifurcations were characteristic of asthma and these findings were more remarkable in the central airways than in the peripheral airways. Various pulmonary function tests-spirogram, flow-volume curve, closing volume, respiratory resistance-were performed soon after examining SAB. The degree of spastic narrowing and stenosis at bifurcations correlated well with FVC, FEV1.0 and V50. These three parameters seemed to be useful in deciding the severity of asthma. The value of these parameters were lower in cases complicated with chronic inflammations and pulmonary emphysema.<br>The degree of these bronchial findings showed a tendency to correlate with MMF and V25. As MMF and V25 values were low in asthmatics with severe lesions in the central airways, these were thought not to reflect the disorder of the peripheral airway alone.<br>There was no correlation between bronchial changes and CV/VC(%). Closing Volume, however, seemed to be an indicative test. CV/VC(%) value was abnormal and the slope of phase III (alveolar plateau) was slanting in most of the cases.<br>The respiratory impedance by 3Hz oscillation technique was not correlative with severity of bronchial lesions, but it showed over 3cmH2O/1tr/sec in most of the cases and this test seemed to be appropriate for screening.
収録刊行物
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- 日本胸部疾患学会雑誌
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日本胸部疾患学会雑誌 16 (3), 173-179, 1978
社団法人 日本呼吸器学会