肝不全に対するhemoperfusionの治療経験  [in Japanese] Hemoperfusion for the treatment of hepatic failure  [in Japanese]

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Abstract

最近われわれは, 肝不全7症例に対して, hemoperfusion (HP) を施行したので報告する.<br>著効例は口腔外科術後2週, 1例, 有効例は肝硬変および食道静脈瘤術後3ヵ月の1例でその他, 心臓弁膜疾患術直後3例, 肝硬変および肝癌術直後1例, 食道癌術直後1例は無効であった. HP著効, 有効例と無効例で11の検査項目で比較検討を加えた. 著効, 有効例では有意に総ビリルビン値 (T bil値) は低値であり, また統計的には有意でないが, GOT値, 血小板数も低値の傾向を認めた. その他, Choline-esterase値 (Ch-E値), Prothrombin time値等については明らかな差を認めなかった.

We report seven cases of hepatic failure who were treated with hemoperfusion. Two out of the seven showed improvement of consciousness, although there was no chance in the other five. We divided these patients into two groups, namely the responding group and the non-responding group. Analysis of various clinical data including LDH, serum GOT, GPT, alkaline phosphatase hematocrit, platelet, fibrinogen level and choline esterase, revealed no significant differences between the two. However, total bilirubin level in the responding group was 14.8±0.8mg/d<i>l</i> while thet in the non-responding group was 39.0±10.7mg/d<i>l</i> which was significantly higher (p<0.1).

Journal

  • Journal of Japanese Society for Dialysis Therapy

    Journal of Japanese Society for Dialysis Therapy 16(3), 145-148, 1983

    The Japanese Society for Dialysis Therapy

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