肺大細胞がん切除例の臨床像と手術成績  [in Japanese] Clinical aspects of surgically treated large cell carcinomas of the lung.  [in Japanese]

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Abstract

肺大細胞癌切除例97例につき, 臨床的検討を行った.X線像では原発巣型が93.8%を占め, その過半数が径4cmを越えていたにもかかわらず, ブロンコファイバースコピーにて腫瘍可視が24.7%と少なかった.このことは, 大細胞癌には末梢発生が多いことを示唆している.p-TNM病期I期が40例 (41.2%), III期が46例 (47.4%) と, 進行例がやや多い傾向にあったが, 絶対的治癒切除後の5年生存率は53.1%と比較的良好であった.早期に切除すれば良好な成績が望めるものと考えられた.

Clinical features and post-operative results of 97 resected large cell carcinomas of the lung were studied. X-ray findings showed a tumor type in 91 out of 97, 93.8%, and the diameter or the tumor was larger than 4 cm in 53.8%. However, the tumor was visible by bronchofiberscopy in only 24.7%. These clinical features suggest that most of the large cell carcinomas arise from the periphery of the lung and grow rapidly.<BR>By p-TNM stage classification, 40 out of 97 (41.2%) were stage 1, and 46 (47.4%) were stage 3. The stage of the disease in patients with large cell carcinoma was slightly more advanced than adenocarcinoma and squamous cell carcinoma. However, the post-operative longterm survival rates after curative and relatively curative resection in large cell carcinoma, were situated between those of squamous cell carcinoma and adenocarcinoma, showing no significant differences. The five-year survival rate of large cell carcinomas after curative resections was 53.1%, while it was 28.5% after relatively curative resections. Post-operative results of non-curative resection were significantly poorer in large cell carcinoma comparing with adenocarcinoma and squamous cell carcinoma. Therefore, it is concluded that the post-operative results of large cell carcinoma can be expected to be fairly good, if they are detected and resected at an early stage.

Journal

  • Haigan

    Haigan 26(3), 267-277, 1986

    The Japan Lung Cancer Society

Codes

  • NII Article ID (NAID)
    130003754138
  • Text Lang
    JPN
  • ISSN
    0386-9628
  • Data Source
    J-STAGE 
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