A case of adenoid cystic carcinoma of the parotid gland. An immunohistological study.

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  • 高山 泰男
    1st Department of Oral Surgery, Nihon University School of Dentistry
  • 鈴木 円
    1st Department of Oral Surgery, Nihon University School of Dentistry
  • 白野 隆史
    1st Department of Oral Surgery, Nihon University School of Dentistry
  • 山野井 弘充
    1st Department of Oral Surgery, Nihon University School of Dentistry
  • 堀 稔
    1st Department of Oral Surgery, Nihon University School of Dentistry
  • 田中 博
    1st Department of Oral Surgery, Nihon University School of Dentistry
  • 草間 薫
    Department of Pathology, Nihon University School of Dentistry
  • 茂呂 周
    Department of Pathology, Nihon University School of Dentistry

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  • An Immunohistological Study

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We treated a case of adenoid cystic carcinoma that occurred in the right parotid gland of a 51-year-old woman. Although the tumor, including part of the parotid gland, was resected based on a clinical diagnosis of pleomorphic adenoma, it was later diagnosed as adenoid cystic carcinoma of mixed cribriform-solid type by histopathological examination after resection. Therefore, postoperative irradiation with a dose of 51 Gy was performed.<BR>Immunohistological examination of the resected specimen showed that the profiles of carbohydrate antigens were Lewis (a-, b+) in both the tumor and surrounding normal parotid tissue. NCC-SG-007 antigen was observed in the tumor tissue but not in the normal parotid gland, suggesting that this antigen was associated with the tumor.

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