Medical and Biochemical Application of Infrared Spectroscopy. VII. Studies on Various Animal Bile by Infrared Spectra and Some of its Pharmaceutical Application, Including Identification of the Bear Bile (Yutan)

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A large number of bile from 18 kinds of animals were submitted to infrared spectral measurement and it was revealed that these spectra were very effective in knowing various bile components and constituents of bile acids. This method was successfully utilized in discriminating Yiatan (bear bile), used as the valuable home remedy in the Orient from olden times, from the bile of other animals.<BR>Some results different from past reports were obtained; notably that the main component of carp bile is not bile acid but is a sulfate of bile alcohol and that the conjugate amino acid in the bile acids of some fish was not taurin.<BR>Infrared spectra of bile from about 100 dogs were examined as basis for the study of pharmacological action of choleretics. Infrared spectrum of dog bile is especially distinct, there is no necessity of considering individual differences, and there are no variation in the amount of bile outflow or infrared spectrum even eight hours after the operation.

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