Synthesis of 2-Methyl-3-oxa-A-norestra-1, 5 (10)-dien-17β-ol and 2-Methyl-3-oxa-4, 19-bisnorpregna-1, 5 (10)-dien-20-one

• KOMENO TAICHIRO

  Shionogi Research Laboratory, Shionogi & Co., Ltd.

• ITANI HIKARU

  Shionogi Research Laboratory, Shionogi & Co., Ltd.

抄録

The titled compounds were synthesized from the corresponding 10-propargyl-des-A-9 (10)-en-5-one derivatives through the 3, 5-seco-4-nor-dioxo steroids. The preparation of des-A-19-norpregn-9 (10)-ene-5, 20-dione involving the condensation of phenyl methyl sulfone or dimethyl sulfone with methyl 1β-methoxycarbonyl-5, 5-ethylenedioxy-7amethyl-3aα, 7aβ-hexahydroindan-4x-yl propionate is also described.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 21 (2), 335-345, 1973

  公益社団法人 日本薬学会

キーワード

• Drug Discovery
• General Chemistry
• General Medicine

詳細情報

• CRID: 1390001204171844224
• NII論文ID: 130003767051
• DOI: 10.1248/cpb.21.335
• ISSN: 13475223
• ISSN: 00092363
• Web Site: http://www.jstage.jst.go.jp/article/cpb1958/21/2/21_2_335/_pdf
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可