Chemical and biochemical studies on carbohydrate esters. V. Anti ehrlich ascites tumor effect and chromatographic behaviors of fatty acyl monoesters of sucrose and trehalose.
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抄録
Accrding to the procedure of Osipow, sucrose was partially acylated with palmitic, stearic, hydnocarpic, and ricinoleic acids. In the similar manner, the selective esterification of trehalose was performed, using caprylic, lauric, myristic, and stearic acids. The ester compositions of the resulting preparations were preliminarilly analysed by means of thin-layer chromatography and gas chromatography, and the major components contained in them were tentatively assigned to the 6-monoesters of these disaccharides. All the preparations obtained proved to exert considerable antitumor effect against Ehrlich ascites carcinoma in mice by intraperitoneal administration.
収録刊行物
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- CHEMICAL & PHARMACEUTICAL BULLETIN
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CHEMICAL & PHARMACEUTICAL BULLETIN 25 (7), 1717-1724, 1977
公益社団法人 日本薬学会
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詳細情報 詳細情報について
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- CRID
- 1390282679147245952
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- NII論文ID
- 110003622632
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- NII書誌ID
- AA00602100
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- ISSN
- 13475223
- 00092363
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- PubMed
- 908095
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可