Timed-release of mitomycin C from its agarose bead conjugate.

• 橋田 充

• 小嶋 拓巳

• 高橋 嘉輝

• 村西 昌三

• 瀬崎 仁

抄録

A new derivative of mitomycin C, mitomycin C-agarose bead conjugate, was synthesized by using cyanogen bromide method. Biologically active mitomycin C was released successively from the conjugate with a half-life of about 6 day in vitro, and also in vivo following subcutaneous injection of conjugate.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 25 (9), 2456-2458, 1977

  公益社団法人 日本薬学会

キーワード

• cancer chemotherapy

詳細情報

• CRID: 1390001204169365632
• NII論文ID: 110003622747
• NII書誌ID: AA00602100
• DOI: 10.1248/cpb.25.2456
• ISSN: 13475223
• ISSN: 00092363
• Web Site: http://www.jstage.jst.go.jp/article/cpb1958/25/9/25_9_2456/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1978107414
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可