Antiinflammatory principles of Atractylodes rhizomes.

• 遠藤 勝也

• 田口 貴士

• 田口 芙美子

• ヒキノ ヒロシ

• 山原 條二

• 藤村 一

抄録

The crude drug"jutsu"prepared from Atractylodes rhizomes has been used for antiinflammatory purposes in Oriental medicine. In fact, a preparation from A. japonica was found to show significant inhibition of the increased vascular permeability induced by acetic acid. Fractionation of the extract, monitoring by bioassay, resulted in the isolation of two active principles, (+)-eudesma-4 (14), 7 (11)-dien-8-one (VI) and atractylenolide I (VII). The structurally related principles atractylenolide II and III (VIII and IX) also had the tendency to show antiinflammatory activity.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 27 (12), 2954-2958, 1979

  公益社団法人 日本薬学会

キーワード

• antiinflammatory activity

詳細情報

• CRID: 1390001204163950464
• NII論文ID: 110003623558
• NII書誌ID: AA00602100
• DOI: 10.1248/cpb.27.2954
• COI: 1:CAS:528:DyaL3cXhsVSmsr0%3D
• ISSN: 13475223
• ISSN: 00092363
• ISSN: http://id.crossref.org/issn/00092363
• PubMed: 540333
• Web Site: http://www.jstage.jst.go.jp/article/cpb1958/27/12/27_12_2954/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1980110851
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可