Triazolo[4,5-d]pyrimidines. IV. The Grignard reaction of 3-substituted 3H-1,2,3-triazolo[4,5-d]pyrimidines.

• 東野 武郎

• 香取 達彦

• 吉田 静生

• 林 英作

抄録

Grignard reactions of 3-methyl- (1m) and 3-phenyl-3H-1, 2, 3-triazolo [4, 5-d] pyrimidine (1p) resulted in the formation of 7-alkyl-6, 7-dihydro-3-methyl- (2m) and 7-alkyl-6, 7-dihydro-3-phenyl-3H-1, 2, 3-triazolo [4, 5-d] pyrimidines (2p) in moderate yields. These dihydro compounds 2m and 2p were converted into 7-alkyl-3-methyl- (3m) and 7-alkyl-3-phenyl-3H-1, 2, 3-triazolo [4, 5-d] pyrimidines (3p), respectively, by oxidation with potassium ferricyanide.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 27 (12), 3176-3179, 1979

  公益社団法人 日本薬学会

キーワード

• 3-substituted 7-alkyl-3H-1, 2, 3-triazolo [4, 5-d] pyrimidines

詳細情報

• CRID: 1390282679143106048
• NII論文ID: 110003623595
• NII書誌ID: AA00602100
• DOI: 10.1248/cpb.27.3176
• ISSN: 13475223
• ISSN: 00092363
• Web Site: http://www.jstage.jst.go.jp/article/cpb1958/27/12/27_12_3176/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1980110692
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可