Studies on 13C magnetic resonance spectroscopy. XII. 13C and 1H NMR of 5-substituted pyrimidine derivatives.

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^<13>C and 1H nuclear magnetic resonance chemical shifts of 5-substituted pyrimidine derivatives were measured. The linear correlations of the chemical shifts between 5-substituted pyrimidines vs. monosubstituted benzenes, 3-substituted pyridines or substituent constants were revealed, and the chemical shift of pyrimidine derivatives can be predicted by the additivity rule.

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