The influence of bovine thymus hypocalcemic protein, TP1, on the levels of cyclic nucleotides in murine thymus lymphocytes.

• 平松 礼司

• 水谷 隆治

• 水谷 彰

抄録

The effects of bovine thymus hypocalcemic protein (TP1) on cAMP and cGMP levels in murine thymus cells were studied. TP1 elevated cGMP levels 12.5-fold at a concentration of 0.15 mg/ml after incubation for 5 min but the amount of cAMP in thymocytes was lowered. These results suggest that TP1 stimulates the differentiation of early T-cells to mature T-cell subsets, such as helper cells, but does not stimulate that of stem cells to early T-cells.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 28 (2), 413-416, 1980

  公益社団法人 日本薬学会

キーワード

• thymic hormone

詳細情報

• CRID: 1390282679143472512
• NII論文ID: 110003623919
• NII書誌ID: AA00602100
• DOI: 10.1248/cpb.28.413
• ISSN: 13475223
• ISSN: 00092363
• PubMed: 6248256
• Web Site: http://www.jstage.jst.go.jp/article/cpb1958/28/2/28_2_413/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1981021005
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可