Shape-transforming action of myrmicacin (3-hydroxydecanoic acid) and some related compounds on the membrane of intact human erythrocytes.

• 金保 安則

• 佐藤 隆司

• 藤井 達三

• 岩波 洋造

• 岩垂 司

• 折登 一彦

抄録

The effects of the following compounds (most of which had been proved to inhibit mitotic progression of pollens) on the shape of the membrane of human erythrocytes were tested : myrmicacin (3-hydroxydecanoic acid) and its derivatives, even-numbered C_4-10 fatty acids, and some C₁₀ diols. They all induced a shape change of the membrane-exvagination (crenation) type at pH 7.4 to different extents, depending on their structures, but not at pH 6.0. The shape change induced was reversible. The structure-activity relationship and the mode of action were compared with those for the action of these compounds on pollen growth.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 29 (10), 3063-3066, 1981

  公益社団法人 日本薬学会

キーワード

• mitotic progression

詳細情報

• CRID: 1390282679138885632
• NII論文ID: 110003633538
• NII書誌ID: AA00602100
• DOI: 10.1248/cpb.29.3063
• COI: 1:CAS:528:DyaL38Xms1ehtA%3D%3D
• ISSN: 13475223
• ISSN: 00092363
• PubMed: 7318031
• Web Site: http://www.jstage.jst.go.jp/article/cpb1958/29/10/29_10_3063/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1982211743
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可