Studies on microcapsules. I. Role and effect of coacervation-inducing agents in the microencapsulation of ascorbic acid by a phase separation method.
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The role and effect of coacervation-inducing agents such as butyl rubber, polyethylene and polyisobutylene in microencapsulation were investigated by using phase separation from cyclohexane solution with change of temperature. Ascorbic acid was used as a core material and ethylcellulose was used as a wall-forming material. Among the three different coacervation-inducing agents, polyisobutylene was suitable for microencapsulation, resulting in low aggregation of microcapsules and a slow dissolution rate. The role of coacervation-inducing agents in microencapsulation was investigated with polyisobutylene. Polyisobutylene changed the gel into a coacervate and resulted in the formation of smooth and thick-walled microcapsules. It also largely prevented the aggregation of microcapsules.
収録刊行物
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- CHEMICAL & PHARMACEUTICAL BULLETIN
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CHEMICAL & PHARMACEUTICAL BULLETIN 30 (8), 2894-2899, 1982
公益社団法人 日本薬学会
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詳細情報 詳細情報について
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- CRID
- 1390282679140951168
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- NII論文ID
- 110003634691
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- NII書誌ID
- AA00602100
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- ISSN
- 13475223
- 00092363
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- PubMed
- 7139831
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可