Complex formation of zinc(II) ion with glycyclglycyl-L-histidine: An investigation by proton nuclear magnetic resonance spectroscopy.

• 上田 順市

• 花木 昭

• 吉田 直子

• 中嶋 暉躬

抄録

A proton nuclear magnetic resonance (¹H-NMR) study of the interaction of zinc(II) ion with glycylglycyl-L-histidine (Gly-Gly-His) was carried out. The addition of zinc(II) ion affected the NMR spectrum of Gly-Gly-His above pH 6; the signal of the imidazole C-2 proton underwent line broadening and upfield shift, and that of the methylene proton of glycine at the amino terminal was also shifted upfield. It is suggested that Gly-Gly-His functions as a bidentate ligand, coordinating with the zinc(II) ion through the amino nitrogen and the neighboring peptide oxygen, and that the imidazole nitrogen of the complex is linked intermolecularly to the zinc(II) ion of another peptide complex.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 34 (3), 1315-1318, 1986

  公益社団法人 日本薬学会

キーワード

• metal-ligand interaction

詳細情報

• CRID: 1390001204165506432
• NII論文ID: 130003770619
• DOI: 10.1248/cpb.34.1315
• COI: 1:CAS:528:DyaL28XktlOks7k%3D
• ISSN: 13475223
• ISSN: 00092363
• Web Site: http://www.jstage.jst.go.jp/article/cpb1958/34/3/34_3_1315/_pdf
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可