歯周炎由来細菌に対するミノサイクリンの感受性

• 金子 明寛

  富士フィルム健康管理センター歯科

• 河野 誠之

  あさひ銀行健康管理センター歯科

• 和田 信行

  東海大学医学部口腔外科

• 小林 寅〓

  三菱化学ビーシーエル化学療法研究室

書誌事項

タイトル別名

• Susceptibility of minocycline to causative organisms of periodontal disease.

抄録

Minocycline has been frequently inserted topically into the periodontal pocket of periodontal disease. The causative organisms of periodontal disease were collected from clinical cases. Twenty strains of Prevotella intermedia, 20 strains of Porphyromonas gingivalis, 20 strains of Capnocytophaga sp., 20 strains of Fusobacterium nucleatum, 15 strains of Eikenella corrodens, and 15 strains of Actinobacillus actinomycetemcomitans were identified and stocked. MICs of minocycline were measured for those organisms. MIC ranges and MIC₉₀ were as follows : Prevotella intermedia (≤0.025-3.13, 1.56), Porphyromonas gingivalis (≤0.025-1.56, 0.39), Capnocytophaga sp. (0.05-0.2, 0.10), Fusobacterium nucleatum (≤0.025-3.13, 0.10), Eikenella corrodens (0.2-1.56, 0.78), and Actinobacillus actinomycetemcomitans (0.39-0.78, 0.78) .<BR>To evaluate therapeutic agents for periodontal disease, one should measure the susceptibility of causative organisms and the effusion level in periodontal pockets.<BR>Minocycline maintained favorable susceptibility to organisms of periodontal disease.

収録刊行物

• 歯科薬物療法

  歯科薬物療法 16 (2), 87-89, 1997

  日本歯科薬物療法学会

キーワード

• ミノサイクリン
• 歯周炎ポケット
• 歯周炎
• 感受性

詳細情報

• CRID: 1390001204729847424
• NII論文ID: 130003840766
• NII論文ID: 10010923391
• NII書誌ID: AN0023517X
• DOI: 10.11263/jsotp1982.16.87
• ISSN: 18844928
• ISSN: 02881012
• Web Site: https://search.jamas.or.jp/link/ui/1998030794
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可