A diagnostic significance of rapid cytology employed during bronchoscopy under general anesthesia

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  • 全麻気管支鏡下迅速細胞診の診断的意義

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Abstract

A rapid cytology with a quick staining and rapid interpretation employed during bronchoscopy under general anesthesia was evaluated in order to improve a successful diagnostic rate especially in peripheral lung cancer.<BR>The results obtained here were as follows:<BR>1. 84 of the 95 patients with lung cancer yielded a positive diagnostic rate of 88.4%.<BR>2. The improved rate of diagnosis was associated with an increase of positive rate of 16.4% in endoscopically nonvisible tumors, 18.3% in peripherally located tumors and 14% in size of tumor when the diameter was less than 3 cm in 56 resected cases of lung cancer, respectively.<BR>3. The rapid cytology reflected an advantage for securing an accurate diagnosis in endoscopically non-visible small tumors located in the periphery of the lung, as expected.<BR>4. This may be attributed to the fact that a false negative related in part to the skill in the use of flexible fiberoptic bronchoscope under fluoroscopic guidance was avoided by the rapid cytology.<BR>5. Shorr staining available for the rapid cytology was found to be very useful not only for diagnosis of malignancy, but also for accuracy of diagnosis of cell type.

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