ｖｏｎ　Ｒｅｃｋｌｉｎｇｈａｕｓｅｎ病に合併したｍａｌｉｇｎａｎｔ　ｐｅｒｉｐｈｅｒａｌ　ｎｅｒｖｅ　ｓｈｅａｔｈ　ｔｕｍｏｒ（ＭＰＮＳＴ）の１例

• 堀岡 良康

  市立伊丹病院病理

• 辻 求

  市立伊丹病院病理

• 森川 政夫

  大阪医科大学付属病院中検病理

• 荒木 徹也

  市立伊丹病院皮膚科

書誌事項

タイトル別名

• A case of malignant peripheral nerve sheath tumor associated with von Recklinghausen's disease.

抄録

The imprint cytologic features of malignant peripheral nerve sheath tumor (MPNST) are reported. The patient, a 40-year-old woman, with von Recklinghausen's disease noticed a gradually enlarging subcutaneous nodule on the right shoulder. CT revealed the nodule was a tumor, measuring 9 cm in diameter. The imprint smear of the surgically resected tumor consisted of loosely cohesive groups of spindle-shaped cells and isolated cells. Most of the tumor cells had fusiform nuclei with coarse granular chromatin and indistinct, fibrillary cytoplasm, including cells with twisted nuclei and comma-shaped cells. Moreover, some isolated cells showing large and pleomorphic nuclei with granular chromatin and a few multinucleated cells were found. Intranuclear vacuoles were occasionally observed in these anaplastic cells. Histologic sections demonstrated swirling and interlacing fascicle patterns of spindle-shaped cells. Multinucleated and pleomorphic cells with intranuclear vacuoles were also found around the necrotic areas in the tumor. The majority of the tumor cell were positive for S-100 protein immunostaining.

収録刊行物

• 日本臨床細胞学会雑誌

  日本臨床細胞学会雑誌 38 (1), 119-120, 1999

  公益社団法人　日本臨床細胞学会

詳細情報

• CRID: 1390001204690955904
• NII論文ID: 130003926566
• NII論文ID: 110001225640
• NII書誌ID: AN00198721
• DOI: 10.5795/jjscc.38.119
• ISSN: 18827233
• ISSN: 03871193
• Web Site: https://search.jamas.or.jp/link/ui/1999145480
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可