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Abstract

Mutagenic activity, antibacterial activity and enzymatic reducibility of geometrical isomers of several nitrofurans were examined comparatively in Salmonella typhimurium TA100. These biological activities were well correlated to each other, not only between cis and trans isomers of each nitrofuran, but also among all the nitrofurans tested. Furthermore, the reducibility of each pair of cis and trans isomers by the bacterial enzymes also appeared to be correlated to the above biological activities.

Journal

  • Chemical and Pharmaceutical Bulletin

    Chemical and Pharmaceutical Bulletin 32(5), 2036-2039, 1984

    The Pharmaceutical Society of Japan

Codes

  • NII Article ID (NAID)
    130003942792
  • Text Lang
    ENG
  • ISSN
    0009-2363
  • Data Source
    J-STAGE 
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