書誌事項
- タイトル別名
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- Use of Murine Norovirus as a Novel Surrogate to Evaluate Resistance of Human Norovirus to Free Chlorine Disinfection in Drinking Water Supply System
抄録
Human noroviruses (NoVs) are a major cause of viral gastroenteritis outbreaks worldwide and commonly transmitted via the fecal-oral route through contaminated food or water. Due to the lack of cell culture system for NoVs, little knowledge is available on the resistance of NoVs to various disinfectants. In this study, cultivable murine norovirus (MNV) was used as a surrogate to evaluate resistance of NoVs to chlorination in drinking water supply system. MNV, NoV, and poliovirus type 1 (PV1) were inoculated into treated water collected from a drinking water treatment plant, followed by free chlorine disinfection. MNV was inactivated more than 99.99%(4 log) with the Ct value of 3 mg/L-min, showing less resistance to free chlorine than PV1. Based on TaqMan real-time RT-PCR analysis, the reduction rate of NoV genogroup II (Lordsdale strain) was comparable to that of MNV. These results indicate that NoVs are not highly resistant to free chlorine disinfection compared with other enteric viruses and that NoV-infection via drinking water supply system can be controlled with adequate chlorination.
収録刊行物
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- 環境工学研究論文集
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環境工学研究論文集 45 361-370, 2008
公益社団法人 土木学会
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詳細情報 詳細情報について
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- CRID
- 1390001204112321280
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- NII論文ID
- 80019992819
- 130003949613
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- ISSN
- 1884829X
- 13415115
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可