微生物の生産する赤色色素ジデオキシグリセオロジンCの構造解析とペプチド複合体としての実用化

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タイトル別名
  • Structural elucidation of dideoxygriseorhodin C, a red pigment produced by microbe, and utility as pigment-peptide complex.
  • ビセイブツ ノ セイサンスル セキショク シキソ ジデオキシグリセオロジン C

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A red pigment fraction was extracted from the mycelia of an actinomycete, Strept omyces californicus JCM 6910, derived from soil. The fraction was purified by column ch romato-graphies on silica gel and Sephadex LH-20 and was finally purified by reversed p hase HPLC. The purified pigment was identified as a new compound by the analyses of NMR spe ctra and named as dideoxygriseorhodin C. The pigment-peptide complex has potential use as a natural food coloring agent because of its water-solubility. The color tone in a queous solution on pigment-peptide complex showed from red to orangish-red (pH3-5) and showed purplish-red(pH6-9). Its fading was not observed by heating but its colo r tone was affected by sunlight. A red pigment, dideoxygriseorhodin C, was suggested to be safe in the biological tests of acute toxicity and mutagenicity. (Received Feb.17, 1989)

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