新規超音波ネブライザーにおける気管支拡張剤の安定性

DOI

書誌事項

タイトル別名
  • STAIBILITY OF BRONCHODILATERS USING NEW ULTRASONIC NEBULIZER

この論文をさがす

抄録

Ultrasonic nebulization is widely performed for inhaant therapy. But there still remain some problems in the stability of the drugs in inhalant solutions during ultrasonic nebulization. We have reported that the remaining ratios of some bronchodilaters were below 90% after nebulization using the conventional ultrasonic nebulizer.<BR>A new ultrasonic nebulizer has been developed by OMRON. We investigated the effect of the new ultrasonic nebulizer on the stability of bronchodilaters for inhalant therapy. Stability tests were performed on bronchodilaters in terms of visible change, pH and degradation rate of the drug using HPLC after ultrasonic nebulization.<BR>The results may be summarized as follows. The ratios of all bronchodilaters remained at more than 95% after 8 minutes of ultrasonic nebulization using the new ultrasonic nebulizer.<BR>Therefore, bronchodilaters are highly stableusing new ultrasonic nebulizer and should be effective. We concluded that the new ultrasonic nebulizing method can be applied in the inhalant therapy of many inhalant preparations.

収録刊行物

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ