口腔細菌の嫌気的呼吸系発現に係わるFNR様転写制御蛋白質
書誌事項
- タイトル別名
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- FNR-like protein as a regulator for the gene expression of anaerobic respiratory system in oral bacteria.
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TheE. coliFNR protein is known as a molecular oxygene sensor and a specific activator for the gene expression of anaerobic respiratory system. In order to survey metabolic response toward molecular oxygen in oral bacteria from viewpoint of FNR-like protein participation, the expression of FNR-like protein in five representative strains of oral bacteria (Actinobacillus actinomycetemcomitansand Streptococcus sanguis as facultative anaerobe, Wolinella recta as microaerophile, and Prevotella intermedia and Fusobacterium nucleatumas strict anaerobe) was investigated with the Western blot method using an anti-FNR rabbit serum prepared against the purifiedE. coliFNR. For only A. actinomycetemcomitansas a facultative anaerobe, the Western blot test was positive, whereas negative for other four strains. This implies the possibility that in A. actinomycetemcomitans, a regulatory mechanism similar to that in E. coli functions for the expression of anaerobic respiratory genes.<BR>The expression level of FNR-like protein in A. actinomycetemcomitans was found to be enhanced with decreasing rate of the fructose-limited growth at the redox potential fixed around-400 mV, andbe maximum at the redox potential around-250 mV with the growth rate fixed at 0.11 h-1 under the anaerobic conditions.
収録刊行物
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- 歯科基礎医学会雑誌
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歯科基礎医学会雑誌 34 (5), 459-466, 1992
歯科基礎医学会
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詳細情報 詳細情報について
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- CRID
- 1390001204683566336
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- NII論文ID
- 130004001732
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- ISSN
- 03850137
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
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- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可