子馬の下痢症および雌馬の子宮炎由来大腸菌の薬剤感受性について

• 安斉 了

  Epizootic Research Station, Equine Research Institute, Japan Racing Association

• 鎌田 正信

  Epizootic Research Station, Equine Research Institute, Japan Racing Association

• 池 和憲

  Research Center for Veterinary Science, Kitasato Institute

• 兼丸 卓美

  Epizootic Research Station, Equine Research Institute, Japan Racing Association

• 熊埜御堂 毅

  Equine Research Institute, Japan Racing Association

書誌事項

タイトル別名

• Drug Susceptibility of <i>Escherichia coli</i> Isolated from Foals with Diarrhea and Mares with Metritis

抄録

Drug susceptibility tests were carried out by the disk diffusion and agar dilution methods to make a guide for antibiotic treatment of horses with diarrhea or metritis due to Escherichia coli, and to examine the presence of E. coli isolates resistant to a wide range of antimicrobial agents. When 162 isolates of E. coli were examined for drug susceptibility by using 63 kinds of commercial discs, 10% to 30% of them showed the resistance to 13 antibiotics, including streptomycin, kanamycin, tetracycline, ampicillin and chloramphenicol, to which the bacteria might be originally susceptible. When the results of the disc drug sensitivity test were compared between 44 hemolytic and 118 non-hemolytic strains of E. coli, there were little differences in susceptibility to main antimicrobial agents. When the minimal inhibitory concentrations (MICs) of 61 antimicrobial agents were examined with 90 of the isolates described above, all the 90 isolates showed good susceptibility to 18 antimicrobial agents belonging to aminoglycosides, cephems, peptides, nitrofurans and penicillins. The MIC was less than 3.13μg/ml for more than 90% of these isolates. On the contrary, tetracyclines, chloramphenicols and sulfonamides failed to inhibit the growth of more than 90% of the isolates at a concentration of 100μg/ml. Consequently, 3 aminoglycosides (gentamicin, sisomicin and tobramycin) and 5 cephems (cefotaxime, latamoxef, cefoperazone, ceftizoxime and cefotetan), all of which were especially high active agents among those 18 agents, are recommended for use in the treatment of E. coli infections in horses, such as diarrhea in foals and metritis in mares.

収録刊行物

• 日本中央競馬会競走馬総合研究所報告

  日本中央競馬会競走馬総合研究所報告 1987 (24), 42-50, 1987

  日本ウマ科学会

詳細情報

• CRID: 1390001204717004928
• NII論文ID: 130004014173
• DOI: 10.11535/jes1977.1987.42
• ISSN: 18844626
• ISSN: 03864634
• データソース種別:
  • JaLC
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可