アミジノ-L-プロリンの目尻の小じわに対する改善効果

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  • Effects of Amidino-L-proline on Fine Wrinkles at the Eye Corners

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We evaluated effects of a formulation consisting of 5% amidino-L-proline, which has waterholding ability and softening effect on the stratum corneum, on fine wrinkles at the eye corners in Japanese women in comparison with a placebo depleted of amidino-L-proline only. These formulations were applied twice daily for 6 weeks and fine wrinkles was assessed after 6 weeks of treatments. In evaluation using photo standards, a significant improvement of fine wrinkles was observed in the amidino-L-proline group in contrast to no change in the placebo group. This improvement of fine wrinkles was accompanied by significant increases in both skin elasticity and water content of the stratum corneum. These results indicate that the formulation consisting of 5% amidino-L-proline is useful in reducing the fine wrinkles at the eye corners. Skin Research, 1: 355-362, 2002

収録刊行物

  • 皮膚の科学

    皮膚の科学 1 (5), 355-362, 2002

    日本皮膚科学会大阪地方会・日本皮膚科学会京滋地方会

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