泌尿器科領域の各種膀胱炎に対するPipemidic acidの使用経験 CLINICAL EXPERIENCES OF PIPEMIDIC ACID ON URINARY TRACT INFECTIONS
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Forty-two patients suffering from acute and chronic cystitis were treated with pipemidic acid (PPA).<BR>PPA was administered orally at the dosage of 375-1, 000 mg for 7 days. Of 10 patients with acute simple cystitis, clinical responses were satisfactory in all patients. Of 17 patients with chronic simple cystitis, good responses were seen in 15 patients, poor in 2, and of 15 patients with chronic complicated cystitis, good in 10 patients and poor in 5.<BR>The overall efficacy rate was 83. 3 %. Out of 42 strains, 33 strains (78.6 %) were disappeared, 2 strains (4.8 %) were decreased, 6 strains (14.3 %) were unchanged and only one was substituted.<BR>As for side effects, nausea was observed in 4 patients and exanthema in 2 patients.
CHEMOTHERAPY 23(9), 3115-3120, 1975
Japanese Society of Chemotherapy