耳鼻咽喉科領域感染症に対するAM-715の使用成績 CLINICAL EXPERIENCE OF AM-715 IN THE OTORHINOLARYNGOLOGICAL INFECTIONS

Access this Article

Author(s)

Abstract

耳鼻咽喉科領域化膿性疾患20例を対象にAM-715の臨床効果を検討した。<BR>1) 各疾患別の本剤の有効率は, 急性中耳炎100%, 慢性中耳炎急性増悪100%, 急性扁桃炎83%, 慢性副鼻腔炎, 耳節および鼻節もそれぞれ100%で, 総合有効率は90%であった。<BR>2) 副作用は副鼻腔炎の1例で認められた。AM-715投与開始2日目に浮動性眩暈感を訴えたが, 本剤投与を中止すると症状は消失した。<BR>AM-715は中耳炎症例にはきわめて効果的であるが, 扁桃炎の主な原因である溶連菌に対する抗菌力からは臨床効果に疑問が残る。

The present study was carried out to evaluate clinical effectiveness of AM-715 with 20 cases of suppurative diseases in the field of otorhinolaryngology.<BR>The efficacy rate for each disease was as follows: 100% in acute otitis media, 100% in acute exacerbation of chronic otitis media, 100% in acute exacerbation of chronic sinusitis and 83% in acute tonsillitis.<BR>With regard to side effect, only one patient with acute sinusitis had a feeling of dizziness on the second day after commencement of administration of AM-715, but the dizziness disappeared when the treatment was discontinued.<BR>AM-715 is considered to be excellently effective for the treatment of otitis media, although its antibacterial activity against <I>Streptococcus</I> which is the main causative pathogen of tonsillitis seems doubtful.

Journal

  • CHEMOTHERAPY

    CHEMOTHERAPY 29(Supplement4), 762-765, 1981

    Japanese Society of Chemotherapy

Codes

  • NII Article ID (NAID)
    130004071701
  • NII NACSIS-CAT ID (NCID)
    AN00186653
  • Text Lang
    UNK
  • ISSN
    0009-3165
  • NDL Article ID
    2477465
  • NDL Source Classification
    SC651(耳鼻咽喉科学)
  • NDL Source Classification
    ZS47(科学技術--医学--治療医学・看護学・漢方医学)
  • NDL Call No.
    Z19-42
  • Data Source
    NDL  J-STAGE 
Page Top