TA-058の使用経験
書誌事項
- タイトル別名
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- CLINICAL STUDIES OF TA-058
抄録
TA-058, a new semisynthetic penicillin derivative, has a broad antibacterial spectrum against gram-positive and gram-negative bacteria and also a potent bactericidal activity. Clinical evaluation of the drug in 9 cases of surgical infections was studied (3 with postoperative wound infection, one with intraabdominal abscess, one with intractable abdominal wall fistula, 3 with perineal infection after Miles' op. and one with pneumonia).<BR>1.0 g of TA-058 was administered twice a day for 5-21 days by intravenous injection or intravenous drip infusion.<BR>The results of clinical response were good in 6 cases, fair in one case and poor in 2 cases, Clinical efficacy rate was 66.7%.<BR>In bacteriological response, 2 strains of Peptococcus, each one of α-Streptococcus, E. coli, E. cloacae, Neisseriaceae sp. and P.morganii were eradicated. 2 strains of S. aureus, one of E.coli and P. mirabilis were decreased. One strain of S. aureus, S. marcescens and B.fragilis remained unchanged. Eradication rate was 50.0 %.<BR>No Side effects nor adverse reactions on clinical laboratory findings attributable to the drug were observed.
収録刊行物
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- CHEMOTHERAPY
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CHEMOTHERAPY 32 (Supplement2), 538-542, 1984
公益社団法人 日本化学療法学会
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詳細情報 詳細情報について
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- CRID
- 1390001206283819264
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- NII論文ID
- 130004071976
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- ISSN
- 18845894
- 00093165
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- データソース種別
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- JaLC
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可